| # | Swimmer | Team | Seed | Time | Diff |
| 1 |
Zeldis, Lynzey P (14)
|
MDASC |
5:30.36 |
5:34.38 |
4.02 |
| 2 |
Williams, Margaret A (13)
|
MDBAY |
5:41.42 |
5:44.17 |
2.75 |
| 3 |
Martin, Caroline M (13)
|
MDASC |
5:51.40 |
5:48.51 |
-2.89 |
| 4 |
Ward, Logan O (13)
|
MDASC |
5:53.57 |
5:54.66 |
1.09 |
| 5 |
Jimenez, Nayla P (14)
|
MDASC |
5:36.27 |
5:57.96 |
21.69 |
| 6 |
Broyles, Abigail L (13)
|
MDBAY |
6:08.11 |
6:00.30 |
-7.81 |
| 7 |
Higgins, Charlotte K (14)
|
MDBAY |
6:23.98 |
6:17.24 |
-6.74 |
| 8 |
Schweikert, Elizabeth E (13)
|
MDASC |
6:42.47 |
6:19.23 |
-23.24 |
| 9 |
Acker, Julia A (14)
|
MDASC |
6:34.24 |
6:45.39 |
11.15 |
| 10 |
Karasiewicz, Austyn S (14)
|
MDBAY |
6:32.16 |
6:52.32 |
20.16 |
| 11 |
Sharpe, Zadie (13)
|
MDBAY |
|
7:06.99 |
- |
| 12 |
McGrath, Ivy E (13)
|
MDASC |
7:08.12 |
7:08.29 |
0.17 |
| 13 |
Bagley, Katelyn D (14)
|
MDESA |
|
7:58.03 |
- |