| # | Swimmer | Team | Seed | Time | Diff |
| 1 |
Iorio, Sophia G (12)
|
MDFSC |
2:49.28 |
2:32.10 |
-17.18 |
| 2 |
Bell, Kaitlyn H (12)
|
MDFSC |
2:36.38 |
2:32.52 |
-3.86 |
| 3 |
Shatzer, Madison L (11)
|
MDHAGY |
2:40.44 |
2:37.19 |
-3.25 |
| 4 |
Klaus, Leah M (11)
|
MDEST |
2:37.60 |
2:38.38 |
0.78 |
| 5 |
Pohlhaus, Ayla B (11)
|
MDEST |
2:42.65 |
2:40.79 |
-1.86 |
| 6 |
Matanoski, Genevieve A (11)
|
MDEST |
2:39.04 |
2:41.94 |
2.90 |
| 7 |
Good, Georgia L (12)
|
MDFAST |
2:44.21 |
2:44.06 |
-0.15 |
| 8 |
Gazelle, Amanda E (11)
|
MDRAC |
2:45.98 |
2:44.80 |
-1.18 |
| 9 |
Vandewinckel, Olivia A (11)
|
MDGBSA |
2:52.49 |
2:46.61 |
-5.88 |
| 10 |
Wollenweber, Olivia B (12)
|
MDEST |
2:52.90 |
2:49.15 |
-3.75 |
| 11 |
Harshman, Madeline M (11)
|
MDFAST |
2:52.17 |
2:49.75 |
-2.42 |
| 12 |
Mo, Katina (11)
|
MDEST |
2:55.33 |
2:55.84 |
0.51 |
| 13 |
Keating, Morgan R (12)
|
MDRAC |
2:55.68 |
2:57.22 |
1.54 |
|
Healy, Rian E (11)
|
MDASC |
2:38.74 |
NS |
- |
|
Carris, Ellie M (12)
|
MDRAC |
2:42.12 |
NS |
- |