| # | Swimmer | Team | Seed | Time | Diff |
| 1 |
Sykes, Emily J (19)
|
SEUN! |
4:58.12 |
5:10.05 |
11.93 |
| 2 |
Raasch, Karli N (14)
|
MAFSSC |
|
5:27.83 |
- |
| 3 |
Jia, Katherine X (13)
|
MAUDAC |
5:56.08 |
5:33.74 |
-22.34 |
| 4 |
DiCamillo, Lauren T (17)
|
MACAA |
5:40.89 |
5:35.04 |
-5.85 |
| 5 |
Ehrnfeldt, Megan E (14)
|
MABYNS |
5:48.43 |
5:41.65 |
-6.78 |
| 6 |
Kapp, Christine O (14)
|
MAYY |
5:44.01 |
5:42.15 |
-1.86 |
| 7 |
Turner, Sara C (14)
|
MAEPAC |
5:42.87 |
5:42.98 |
0.11 |
| 8 |
Ladd, Madeline R (15)
|
MACAA |
5:47.37 |
5:43.24 |
-4.13 |
| 9 |
Vorobyeva, Arina I (11)
|
MAUDAC |
5:52.55 |
5:51.08 |
-1.47 |
| 10 |
DiCamillo, Jordyn (15)
|
MACAA |
5:39.65 |
5:51.79 |
12.14 |
| 11 |
Reed, Emma E (16)
|
MAEPAC |
5:56.00 |
5:58.69 |
2.69 |
| 12 |
Behling, Clara A (12)
|
MAFCA |
|
6:01.34 |
- |
| 13 |
Suko, Anya F (14)
|
MACBST |
6:49.22 |
6:01.42 |
-47.80 |
| 14 |
English, Chloe L (12)
|
MAFCA |
6:36.53 |
6:03.79 |
-32.74 |
| 15 |
Crew, Eliana M (13)
|
MATOPS |
6:07.91 |
6:05.27 |
-2.64 |
| 16 |
Raser, Emma F (12)
|
MANPAC |
5:56.29 |
6:06.73 |
10.44 |
| 17 |
Suko, Caroline E (12)
|
MACBST |
|
6:15.92 |
- |
| 18 |
Clow, Jalyn R (14)
|
MAMARA |
6:42.02 |
6:49.72 |
7.70 |
|
Havice, Julia J (12)
|
MAYY |
|
DQ |
- |
|
Kellner, Gabriella H (11)
|
MACBST |
|
DQ |
- |