| # | Swimmer | Team | Seed | Time | Diff |
| 1 |
Horner, Cameron E (17)
|
MDHFY |
4:56.30 |
4:59.13 |
2.83 |
| 2 |
Derasmo, Kelly A (18)
|
PVFISH |
5:09.44 |
5:17.45 |
8.01 |
| 3 |
Buda, Lucy E (17)
|
PVMSSC |
5:21.36 |
5:25.50 |
4.14 |
| 4 |
Stubner, Greta M (16)
|
PVRMSC |
5:35.16 |
5:32.30 |
-2.86 |
| 5 |
Hehir-Keys, Ava F (15)
|
PVMSSC |
5:36.29 |
5:37.62 |
1.33 |
| 6 |
Abogadie, Razelle B (16)
|
PVMSSC |
5:41.69 |
5:38.74 |
-2.95 |
| 7 |
Yu, Claire (15)
|
PVMSSC |
5:45.92 |
5:40.18 |
-5.74 |
| 8 |
Boyle, Jaycie L (17)
|
PVRMSC |
5:49.70 |
5:46.81 |
-2.89 |
| 9 |
Austin, Candace A (16)
|
PVUN |
5:25.81 |
5:50.95 |
25.14 |
| 10 |
Clark, Micah S (15)
|
PVDCPR |
5:56.66 |
5:53.62 |
-3.04 |
| 11 |
Randall, Maya E (15)
|
PVDCPR |
6:00.00 |
5:57.62 |
-2.38 |
| 12 |
Waldt, Madeline E (15)
|
MDBAAC |
5:54.35 |
6:00.74 |
6.39 |
| 13 |
Navarrete, Catherine I (15)
|
PVASA |
6:11.09 |
6:25.85 |
14.76 |
|
Figueroa, Kimberly G (15)
|
PVFISH |
5:57.70 |
NS |
- |