| # | Swimmer | Team | Seed | Time | Diff |
| 1 |
El Ghissassi, Ritaj (14)
|
NIUN |
5:13.04 |
5:17.53 |
4.49 |
| 2 |
McCoy, Sophia H (13)
|
ADCPP |
5:47.90 |
5:49.81 |
1.91 |
| 3 |
Boenau, Carlye Ana T (13)
|
ADBFIN |
5:54.70 |
5:50.14 |
-4.56 |
| 4 |
Ricard, Skylar M (13)
|
ADBFIN |
5:47.64 |
5:50.65 |
3.01 |
| 5 |
Michels, Delaney R (13)
|
ADCPP |
5:49.83 |
5:51.16 |
1.33 |
| 6 |
Gayle, Isabella C (13)
|
ADCPP |
6:04.40 |
5:59.51 |
-4.89 |
| 7 |
Huang, Madison Z (13)
|
ADCPP |
6:13.82 |
6:01.78 |
-12.04 |
| 8 |
Antolick, Caroline B (13)
|
ADALBS |
6:05.91 |
6:04.34 |
-1.57 |
| 9 |
Mohamed, Amber H (13)
|
ADALBS |
6:30.05 |
6:05.38 |
-24.67 |
| 10 |
Thompson, Cora A (13)
|
ADBFIN |
6:15.04 |
6:07.25 |
-7.79 |
| 11 |
Winne, Ellen M (14)
|
ADALBS |
5:39.08 |
6:08.91 |
29.83 |
| 12 |
Xue, Nichole Y (13)
|
ADCPP |
6:05.88 |
6:13.01 |
7.13 |
| 13 |
Guha, Mahika (13)
|
ADCPP |
6:27.13 |
6:17.26 |
-9.87 |
| 14 |
Dusseault, Abigail B (14)
|
ADJJSC |
|
6:17.31 |
- |
| 15 |
Greaux, Lauren A (13)
|
ADDELM |
6:13.22 |
6:18.45 |
5.23 |
| 16 |
Grizzard, Cadence S (14)
|
ADALBS |
6:51.95 |
6:26.61 |
-25.34 |
| 17 |
Heckler, Felicity A (13)
|
ADDELM |
6:52.18 |
6:33.80 |
-18.38 |